Evaluation of Enzyme Kinetic Parameters to Produce Methanol Using Michaelis-Menten Equation
نویسندگان
چکیده
منابع مشابه
ESTIMATING THE PARAMETERS OF THE MICHAElIS - MENTEN EQUATION USING SAS
The Michaelis-Menten equation, a rectangular hyperbola with two ~arameters ~o b~ specified, . occurs prominently 1n enzyme k,netlcs." Often, ~n consulting situations we need to (i) obtain estlmates standard errors, and confidence intervals for the unknown parameters, which define this nonlinear model for one set of experimental conditions and (ii) compare the parameter estimates under different...
متن کاملThe 'double' Michaelis-Menten equation: estimation of parameters.
When the concentration dependence of an enzymic reaction or a transport process can be described by the sum of two Michaelis-Menten terms, reliable data that relate reaction rate and substrate concentration can be obtained even when as much as 70 per cent of substrate was consumed during the assay. Each data pair consists of the average reaction rate during an assay and the concentration where ...
متن کاملConformational Nonequilibrium Enzyme Kinetics: Generalized Michaelis-Menten Equation.
In a conformational nonequilibrium steady state (cNESS), enzyme turnover is modulated by the underlying conformational dynamics. On the basis of a discrete kinetic network model, we use an integrated probability flux balance method to derive the cNESS turnover rate for a conformation-modulated enzymatic reaction. The traditional Michaelis-Menten (MM) rate equation is extended to a generalized f...
متن کاملOptimal design for goodness-of-fit of the Michaelis-Menten enzyme kinetic function
We construct efficient designs for the Michaelis-Menten enzyme kinetic model capable of checking model assumption. An extended model, called EMAX model is also considered for this purpose. This model is widely used in pharmacokinetics and reduces to the MichaelisMenten model for a specific choice of the parameter setting. Our strategy is to find efficient designs for estimating the parameters i...
متن کاملA simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.
The summation of the effects of two or more reversible inhibitors of various types on the initial velocity of enzyme systems obeying Michaelis-Menten kinetics is described by the the general relation: (formula: see text) wherein v1,2,3...n is the velocity of reaction in the simultaneous presence of n inhibitors, vi is the velocity observed in the presence of each individual inhibitor, and v0 is...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bulletin of Chemical Reaction Engineering & Catalysis
سال: 2019
ISSN: 1978-2993
DOI: 10.9767/bcrec.14.2.3317.436-442